Cannabis for Arthritis
Written By QuickMedCards. Reviewed by Dr. Shatha Atiya, PsyD. Updated August 7, 2025
Arthritis doesn’t just cause pain. It steals your freedom. Simple things become mountains to climb. Opening a jar, walking up the stairs, or even getting out of bed in the morning.
If traditional treatments haven’t given you the relief you need, you’re not alone. Many people are turning to cannabis for arthritis. Why? It’s a gentler alternative to strong medications or invasive procedures.
Medical cannabis is gaining popularity because patients find it can ease symptoms like joint pain, inflammation, and trouble sleeping. But how does it work, and is it safe for you?
In this article, we break down the science, explain the benefits and risks clearly, and walk you step‑by‑step through how you can qualify for a medical marijuana card.
By the end of this page, you will have the answers to these questions:
- What is arthritis, and how common is it?
- How does cannabis help with arthritis pain?
- What does research say about medical marijuana for arthritis?
- Which type of cannabis products work best for arthritis?
- How can you get medical cannabis for rheumatoid arthritis or osteoarthritis?
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What is arthritis? How common is it?
Arthritis isn’t just one disease. It’s a term for over 100 conditions that cause joint pain or damage. Most types lead to swelling, stiffness, and compromised movement.
According to the Centers for Disease Control and Prevention (CDC), about 58 million adults in the U.S. have arthritis. The risk goes up with age, with more than half of adults over 75 living with the condition.
Osteoarthritis vs. Rheumatoid Arthritis
- Osteoarthritis (OA) is a “wear‑and‑tear” condition in which cartilage breaks down over time. It leads to bone‑on‑bone friction, swelling, and reduced range of motion.
- Rheumatoid arthritis (RA) is an autoimmune disease where the immune system attacks the joint lining. It leads to inflammation, morning stiffness, and in severe cases, joint damage or deformity.
Traditional treatment relies on NSAIDs, disease‑modifying antirheumatic drugs (DMARDs), corticosteroid injections, and, in severe cases, joint‑replacement surgery. Yet, the pain and side effects can still be so intolerable that many patients may struggle to deal with them.
How Cannabis Helps With Arthritis Pain
We all produce chemicals called endocannabinoids. They act like messengers and help manage pain, immunity, mood, and sleep.
Phytocannabinoids in cannabis, especially tetrahydrocannabinol (THC) and cannabidiol (CBD), interact with the same CB₁ and CB₂ receptors to:
- Reduce the release of pro‑inflammatory cytokines.
- Dull pain signals in the spine and brain.
- Improve sleep quality, which indirectly lowers pain perception.
THC and CBD for Arthritis
THC functions differently compared to CBD.
- THC produces euphoria but also has potent analgesic and anti‑spasmodic properties.
- CBD is non‑intoxicating and appears to regulate immune activity and inflammatory mediators.
One major study tested Sativex®, a 1:1 THC to CBD spray, in 58 people with rheumatoid arthritis. Those who used it reported less morning pain and better sleep compared to those who got a placebo. Moreover, participants in the study didn’t experience serious side effects from the treatment.
Evidence: Cannabis for Rheumatoid and Osteoarthritis
Let’s review medical studies on cannabis for rheumatoid arthritis and osteoarthritis.
Marijuana for Rheumatoid Arthritis
A 2020 study of over 10,000 patients found that cannabis may help some people with arthritis feel better. Key findings include:
- Around 20% of people with rheumatologic diseases, including rheumatoid arthritis, said they had used cannabis.
- Cannabis use was linked to reduced pain intensity.
- Among cannabis users, average pain scores dropped from 8.2 to 5.6 on the study’s pain scale.
Cannabis for Osteoarthritis
A 2024 systematic review analyzed studies from 2012 to 2022. It focused on adults with osteoarthritis who used medical cannabis for pain and function.
The review included seven high-quality studies:
- Two randomized controlled trials (RCTs) tested cannabis in a controlled setting.
- Five observational studies tracked real-world cannabis use.
Key findings from the studies include:
- All five observational studies showed less pain, lower opioid use, and, in some cases, better daily function.
- Only one of the two RCTs found that cannabis reduced pain.
Best Cannabis Strains for Arthritis Pain
The following cannabis strains are popular with arthritis patients for symptom relief:
- Harlequin stands out because it delivers mild euphoria and significant pain relief without heavy sedation.
- ACDC provides functional daytime relief for inflammatory pain with almost no intoxication.
- Bubba Kush is an ideal evening strain that eases severe joint pain and promotes deep sleep.
Use our strain matcher tool to find the best strain for you!
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Cannabis Terpenes for Arthritis
Some terpenes in cannabis may help with arthritis pain, for example:
- β-Caryophyllene has a peppery smell and works by binding to CB₂ receptors in the body. In one study, researchers gave this compound to mice with induced arthritis. The results were promising; it significantly reduced arthritis severity and produced strong anti-inflammatory effects.
- Myrcene has an earthy, mango-like scent. It may relax muscles and promote sleep, which can ease nighttime pain.
- Linalool smells like lavender. It may ease pain sensitivity and improve mood.
Oils, Topicals & Creams: What Works?
Topicals and sublingual oils provide relief without smoking or eating cannabis. Each one works differently. So you can select the best option for your joints, routine, and comfort.
Cannabis oil for arthritis (sublingual tincture)
- Best for: Whole‑body inflammatory pain and morning stiffness
- Onset: 15-30 minutes
- Look for terms like: “Full‑spectrum,” “MCT carrier,” and “graduated dropper.”
THC cream for arthritis
- Best for: Localized knee, hand, or spinal facet pain
- Onset: 10-20 minutes
- Look for terms like: “6-10 mg THC per pump” and “emulsified.”
CBD cream for arthritis
- Best for: Daytime relief without intoxication
- Onset: Around 10 minutes
- Look for terms like: “500-1,000 mg CBD,” “broad‑spectrum,” and “menthol.”
Using Cannabis Safely
To use cannabis safely for arthritis, keep these tips in mind:
- Start with a low dose. Many patients begin with 2.5 mg of THC or a 1:1 THC to CBD dose, taken twice a day.
- Check for drug interactions. CBD can raise levels of certain medications like warfarin, some antidepressants, and immunosuppressants by affecting CYP enzymes.
- Be ready for mild side effects. Dry mouth, lightheadedness, and a slight increase in heart rate are common. Psychosis is rare and usually linked to high doses.
- Avoid driving too soon. Always wait at least six hours after inhaling THC and eight hours after ingesting it.
How to Get a Medical Card for Arthritis
Arthritis is a common qualifying condition for a medical marijuana card in many states. The steps may vary slightly by location, but here’s the general process:
- Fill out the Quick Med Cards form and create your account.
- Choose a time for your marijuana evaluation.
- Meet with a doctor online or in person, depending on your state.
- Get certified for medical cannabis if you qualify.
- Apply for your MMJ card through your state’s medical marijuana program.
- Buy cannabis from a licensed dispensary after approval.
Key Takeaways
- Arthritis is common. Around 58 million U.S. adults live with it. Pain, stiffness, and swelling can make daily tasks harder.
- Cannabis targets the source of arthritis pain. THC and CBD interact with CB₁ and CB₂ receptors to reduce inflammation, block pain, and promote better sleep.
- Studies on cannabis for arthritis show real benefits. Some trials and real-world reports show lower pain, less opioid use, and better movement in patients with rheumatoid or osteoarthritis.
- Strains and terpenes matter. Balanced strains, such as Harlequin, ACDC, and Bubba Kush, along with terpenes like β-caryophyllene and myrcene, can enhance relief.
- Products offer options. Oils, THC creams, and CBD topicals for arthritis give flexible dosing without strong highs.
- Use marijuana safely. Start gradually, check for drug interactions, and don’t drive for several hours after using cannabis.
Frequently Asked Questions
Below are answers to common questions on cannabis for arthritis.
Does cannabis cure arthritis?
No. Evidence supports symptom relief, primarily pain and stiffness, but not a cure. Continue DMARDs for rheumatoid arthritis unless advised otherwise.
Can I use CBD alone for rheumatoid arthritis?
High‑CBD oils or creams help some people, but studies suggest even 1-2 mg THC can enhance pain control.
Are edibles better than inhaled cannabis for joint pain?
Edibles provide 6-8 hours of relief, which is ideal for nighttime osteoarthritis pain. Vaporized flower acts within minutes for flare‑ups but fades faster.
Will I fail a drug test if I use CBD cream?
You probably won’t fail if you use a broad-spectrum or isolate CBD cream. These have no detectable THC, so very little gets into your system.
Full-spectrum creams may have trace amounts of THC, however. Therefore, sensitive drug tests might pick that up.
Disclaimer: This article is for educational purposes and is not a substitute for professional medical advice. Talk with a qualified healthcare provider before starting any cannabis therapy, especially if you take prescription medications.
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